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Minimally Invasive Treatments for Prostatic Enlargement

UroLift and Rezūm offer a middle ground between long-term medication and definitive surgery for BPH. Mr. Jesuraj provides honest, balanced guidance on whether these procedures are appropriate for your situation — and where more definitive treatment is the better choice.

Ⓘ AN HONEST STARTING POINT

His personal recommendation for patients suitable for surgical treatment is Aquablation — a procedure with stronger long-term evidence and more durable outcomes. But the decision is always yours, made on the basis of complete information.

Where Minimally Invasive Procedures Fit

Benign prostatic hyperplasia (BPH) causes a spectrum of lower urinary tract symptoms from mild to severely disabling. Treatment options span from lifestyle modification and medication through to definitive surgical procedures.
Minimally invasive procedures like UroLift and Rezūm sit in a specific gap — between long-term medication that has failed or is not tolerated, and more definitive surgical treatment where symptoms are not yet severe enough to warrant it. They offer the appeal of a short, low-risk procedure — but this comes with important trade-offs in terms of durability of benefit, patient selection limitations, and the possibility of needing further treatment.
Understanding where these procedures fit — and where they do not — is essential before making a decision. Mr. Jesuraj believes in giving patients the full picture.

Lifestyle & Watchful Waiting

Fluid management, caffeine reduction, bladder retraining. For mild symptoms with no complications.

Minimally Invasive — UroLift & Rezūm

For men who cannot tolerate medication or in whom it has failed, but where symptoms are not yet severe enough for definitive surgery — or where ejaculatory preservation is an absolute priority.

Medical Therapy

Alpha-blockers (tamsulosin), 5-alpha reductase inhibitors (finasteride), combination therapy. For moderate symptoms.

Definitive Surgical Treatment

Aquablation, TURP, HoLEP — for significant symptoms, large prostates, or when durable long-term relief is the priority.

UroLift — Prostatic Urethral Lift

Mechanical retraction of obstructing prostatic lobes using small permanent implants

HOW IT WORKS

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WHO MAY BE SUITABLE

  • Lateral lobe enlargement — no significant median lobe
  • Prostate volume 30–80ml
  • Moderate symptoms — not in retention
  • Strong wish to preserve ejaculatory function
  • Medically unfit for general anaesthetic
  • Medication not tolerated or ineffective
  • Median lobe enlargement (common — must be excluded by cystoscopy)
  • Prostate volume over 80ml
  • Urinary retention — current or recent
  • Men planning future MRI surveillance for prostate cancer
  • Men prioritising maximal and durable symptom relief

POTENTIAL ADVANTAGES

  • Preserves antegrade ejaculation in most patients
  • Rapid recovery — often home same day
  • No thermal injury to surrounding tissue
  • Can be performed under local anaesthetic
  • Symptom improvement typically within 2–4 weeks

IMPORTANT LIMITATIONS

  • Not suitable for median lobe enlargement — a very common anatomical pattern
  • Not suitable for large prostates (generally over 80ml)
  • Not suitable if urinary retention has occurred
  • Symptom improvement less than TURP or Aquablation
  • Long-term durability uncertain — significant re-treatment rates at 5 years
  • Permanent implants remain in situ — implications for future MRI and any subsequent TURP

Evidence — Durability & Re-treatment (L.I.F.T. Trial)

UroLift vs Rezūm vs Aquablation

An honest comparison across the procedures — including the one Mr. Jesuraj recommends and performs.

Factor UroLift Rezūm Aquablation
Mechanism Mechanical retraction — no tissue removal Steam thermal ablation — tissue destroyed Robotic waterjet — precise tissue excision, no heat
Median lobe ✘ Not suitable ✓ Yes ✓ Yes — any anatomy
Prostate size 30–80ml only 30–150ml All sizes including very large
Anaesthetic Local or GA Local or GA Spinal or general anaesthetic
Post-op catheter Usually none 1–2 weeks required 1–2 days
Time to benefit 2–4 weeks 4–12 weeks Weeks
Ejaculation preserved Most patients Most patients Significantly lower risk than TURP
Key trial evidence L.I.F.T. RCT (vs sham) Rezūm RCT — McVary et al. (vs sham) WATER trial vs TURP · WATER II large prostates
Long-term evidence 5 years — limited beyond this 5 years — industry-sponsored Robust — independent RCT vs TURP
5-year re-treatment ~13% (L.I.F.T.) Reported low — longer-term data awaited Very low — strong durability data
NICE approved Yes Yes (2018) Yes — 2023
Available at Tees Urology Via referral to specialist Via referral to specialist ✓ Mr. Jesuraj performs

Honest Guidance — Not a Procedure Recommendation

Mr. Jesuraj does not perform UroLift or Rezūm. This is a deliberate clinical decision — not a commercial one. He believes that for the majority of men suitable for surgical treatment of BPH, more definitive procedures offer significantly more durable outcomes.
However, minimally invasive procedures have a genuine and important role for men in the specific gap between medical therapy and definitive surgery. This includes men who:

  • Cannot tolerate medication or in whom medication has failed, but whose symptoms are not yet severe enough for Aquablation or TURP
  • Are medically unfit for general or spinal anaesthetic and need an office-based or local anaesthetic procedure
  • Have a strong and absolute preference for ejaculatory preservation as the overriding priority
  • Fully understand and accept the limitations around durability and potential re-treatment

“My job is to ensure every patient fully understands their options, the evidence supporting each, and the honest limitations — including that the WATER and WATER II trial data, which is the most robust independent RCT evidence for any of these procedures, relates to Aquablation versus TURP. In some patients, especially those presenting with retention of urine or high risk of bleeding, I would strongly recommend them to go for TURP or Holmium Laser Enucleation. The choice of treatment should be married up with the needs and wants of the individual patient. If after full discussion a patient chooses UroLift or Rezūm, I will arrange referral to an appropriate specialist. What I will not do is recommend a procedure I believe is less likely to give a durable result without being transparent about that.”
Mr. Manohar Jesuraj, Consultant Urological Surgeon

Interested?

Book a consultation with Mr. Jesuraj to find out if you are a suitable candidate. Appointments available within days.