Treatment / Nesbitt’s Operation for Peyronie’s disease

Operations for Correcting Bend and Injuries to the Penis
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Correction of Peyronie’s Disease: Surgical and Non-Surgical Treatments


Peyronie’s disease is characterized by the formation of fibrous scar tissue inside the penis, leading to a noticeable and sometimes painful bend or curvature during erections. This condition can make sexual activity challenging or impossible. Thankfully, various treatments, both surgical and non-surgical, can address and correct the curvature caused by Peyronie’s disease.

Surgical Procedures for Correcting Peyronie’s Disease:

  1. Nesbit Procedure (Plication Surgery):

    • Description: Removal or pinching of tissue from the side of the penis opposite the plaque, which cancels out the bending effect.
    • Advantages: Simpler procedure with a high success rate.
    • Indications: Best for men with a bend less than 60 degrees and adequate erectile function.
  2. Incision or Excision and Grafting:

    • Description: The plaque is either incised or excised, and the resultant gap is filled with a graft.
    • Advantages: Can correct more severe curvatures.
    • Indications: Typically used for larger plaques or bends more than 60 degrees, especially when plication might result in significant shortening.
  3. Penile Implants:

    • Description: Devices are implanted within the penis to provide rigidity. Can straighten the penis and provide an erection.
    • Advantages: Offers a solution for both curvature and erectile dysfunction.
    • Indications: Best for men with Peyronie’s disease who also have erectile dysfunction.

Non-Surgical Treatment Options:

  1. Medications:

    • Various oral medications, such as Potaba, Vitamin E, Colchicine, and others, have been tried with varying degrees of success.
  2. Injections:

    • Collagenase (Xiaflex): An enzyme that breaks down the scar tissue, allowing the penis to straighten.
    • Interferon: Breaks down fibrous tissue and reduces the curvature.
    • Verapamil: Helps break down scar tissue and decrease curvature.
  3. Traction Devices:

    • Description: Devices that hold the penis in a straightened position for prolonged periods.
    • Advantages: Non-invasive way to reduce curvature and lengthen the penis.
  4. Shockwave Therapy:

    • Description: High-frequency sound waves break down the plaque tissue.
    • Advantages: Non-invasive and can improve erectile function.
  5. Therapeutic Ultrasound:

    • Uses sound waves to break down scar tissue, reducing curvature.


Peyronie’s disease, while challenging, has various treatments to help affected men. The best method depends on the degree of curvature, plaque location, erectile function, and individual patient needs. Regular consultation with a urologist or medical specialist will guide the journey to a more confident and satisfying intimate life

Further reading 

Following comprehensive patient  information leaflets are published by the British Association of Urological Surgeons (BAUS)

Information leaflet on Peyronie’s Disease by BAUS

Information leaflet on Penile Strqaitening Operations  by BAUS